3MT Faculty winner Nicole Free |
“I’m investigating how benign vocal fold lesions change across
time, and if they respond to a patient’s vocal load or to targeted voice
exercises,” Nicole said.
Vocal load refers to how much a person uses their voice and the
activities or ways in which they use their voice.
“Lesions are usually the result of trauma associated with the
person’s vocal load. They often have a significant impact on voice production,
and subsequently on a person's social function and ability to do their job.”
"If lesions do change in response to these factors, the
implication is that some people will not require surgery, which reduces the
surgical burden on the delicate structure of the vocal fold tissue,'' Nicole
said.
Nicole is supervised by Speech Pathologist Dr Debra Phyland, Head, Department of Surgery Professor Julian Smith,
and Professor Joseph Stemple from the University of Kentucky.
Final year medical student and second place winner Aidan Kashyap is exploring therapies to help babies who struggle to breathe in their first moments of life due to underdeveloped lungs, as a result of a condition known as congenital diaphragmatic hernia (CDH).
Aidan’s presentation
likened the supply of vital oxygen to a baby in utero via the umbilical cord to
an astronaut’s spacesuit, which supplies the oxygen that enables them to
breathe in orbit.
“Immediately
clamping the umbilical cord when babies are born, before they begin to breathe
on their own, leaves them with no source of oxygen and poor blood supply to the
heart. It would be just like welcoming an astronaut back from space and
disconnecting them from their life-support before they can get their helmet off
to breathe on their own,” Aidan said.
“Babies,
particularly those with underdeveloped lungs, will benefit from ensuring that
they are breathing – either on their own or with respiratory support – before
the umbilical cord is clamped.”
Supervised by
Associate Professor Ryan Hodges in the Fetal Therapy Research Group, Aidan is
helping to improve outcomes for babies with CDH.
Their approaches
range from therapies that can be given to mothers during pregnancy, to surgery
that can be performed on the fetus before birth, to a simple change to
management at birth that involves keeping the umbilical cord attached for
longer.
Ten PhD
candidates from across the Faculty competed in the 3MT final on Thursday 12
July. 3MT is a national competition that challenges PhD students to communicate
their research to a non-scientific audience in under three minutes.
Professor Nellie
Georgiou-Karistianis, Associate Dean of Graduate Research, acknowledged the
contribution of all finalists to ground-breaking research, with the potential
to not only transform the lives of patients, but of whole communities and our
society.
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