World-first clinical trial could see nasal spray treatment reduce snoring in children

Associate Professor Gillian Nixon

Researchers at Monash Children’s Hospital and the Royal Children’s Hospital are collaborating on a world first clinical trial to see if a simple nasal spray can reduce the need for surgery for snoring in children. 

Publications week ending 7 September 2018

Elective replacement of intravenous cannula in neonates-a randomised trial. Atul Malhotra et al. published in the European Journal of Pediatrics.

Planned private homebirth in Victoria 2000–2015: a retrospective cohort study of Victorian perinatal data. Miranda Davies-Tuck et al. published in BMC Pregnancy and Childbirth.

The NACSTOP trial: A multi‐center, cluster‐controlled trial of early cessation of acetylcysteine in acetaminophen overdose. Anselm Wong et al. published in Hepatology.

Obesity and anthropometric determinants of autonomic control in children with sleep-disordered breathing-which measurements matter

Rosemary Horne et al. published in the International Journal of Obesity.

Overweight and obese children with sleep disordered breathing have elevated arterial stiffness

Rosemary Horne et al. published in Sleep Medicine.

Time to Open Our Eyes? A Challenge to the Role of Polysomnography for Trials in Pediatric Sleep-Disordered Breathing

Gillian Nixon et al. published in the Journal of Clinical Sleep Medicine.

Read article here.

Age Effects on Cerebral Oxygenation and Behavior in Children with Sleep Disordered Breathing

Rosemary Horne et al. published in the American Journal of Respiratory and Critical Care Medicine.

Read article here.

Quality of life and mood in children with cystic fibrosis: Associations with sleep quality

Rosemary Horne et al. published in the Journal of Cystic Fibrosis.

Read article here.

Regional Brain Tissue Changes and Associations with Disease Severity in Children with Sleep Disordered Breathing

Rosemary Horne et al. published in Sleep.

Read article here.

The impact of sleep disordered breathing on cardiovascular health in overweight children

Rosemary Horne, Lisa Walter et al. published in Sleep Medicine.

Read article here.

Back to sleep or not: the effect of the supine position on pediatric OSA: Sleeping position in children with OSA

Lisa Walter et al. published in Sleep Medicine.

Read article here.

Slow wave activity and executive dysfunction in children with sleep disordered breathing

Sarah Biggs et al. published in Sleep & Breathing.

Read article here.

Overweight and obesity adds to behavioral problems in children with sleep disordered breathing

Rosemary Horne et al. published in Sleep Medicine.

Read article here.

Back to sleep- or not: The impact of the supine position in pediatric OSA

Lisa Walter, Rosemary Horne et al. published in Sleep Medicine.

Read article here.

Australasian Sleep Association clinical practice guidelines for performing sleep studies in children

Gillian Nixon et al. published in Sleep Medicine.

Read article here.

What keeps children with cystic fibrosis awake at night?

Rosemary Horne et al. published in the Journal of Cystic Fibrosis.

Read article here.

Periodic limb movements and restless legs syndrome in children with a history of prematurity.

Sarah Biggs, Gillian Nixon et al. published in Sleep Medicine.

Read article here.

How Well Do Children with Cystic Fibrosis Sleep? An Actigraphic and Questionnaire-Based Study

Rosemary Horne et al. published in the Journal of Pediatrics.

Read article here.

Monash paediatric sleep researchers showcased at ASA conference

PhD student Knarik Tamanyan

Researchers from the Ritchie Centre and Department of Paediatrics attended the Australasian Sleep Association Annual Conference in Adelaide last week. 

The group demonstrated that they are leaders in this field of research with their large number of presentations which showcased the breadth of their research. 

Associate Professor Gillian Nixon, Deputy Director of the Melbourne Children's Sleep Centre gave two plenary talks on the consequences of sleep disordered breathing in children while Professor Rosemary Horne participated in a symposium on cardiorespiratory interactions and the role of sleep, arousal and hypoxia from inutero to adulthood and from bench to bedside. 

The Monash researchers, including postdoctoral fellow Dr Lisa Walter, and students Dr Moya Vandeleur and Ms Knarik Tamanyan presented 7 posters  and 4 oral  presentations.  Knarik (pictured) was awarded a travel grant to attend. Postdoctoral research fellow Dr Sarah Biggs chaired the conference.

The Relationship Between Sleep-Disordered Breathing Severity and Daytime Adaptive Functioning in Children with Down Syndrome

Gillian Nixon et al. published in CNS Neuroscience & Therapeutics.

Read article here.

Adherence to Non-Invasive Ventilatory Support

Gillian Nixon published in Caring for the Ventilator Dependent Child.

Read chapter here.