This week's Hudson seminar
will be held in Seminar
Rooms 1 & 2, TRF Building on Thursday 7th June, 12pm-1pm. Our speaker will be Dr Katerina Hortova, PhD.
Group of Reproductive Biology,
Institute of Biotechnology, Czech Academy of Sciences, BIOCEV, Czech Republic;
Department of Zoology, Faculty of Science, Charles University, Prague, Czech
Republic
She will be presenting 'From protein domain dynamics to new diagnostic markers for gamete selection that enhance human assisted reproduction success'
Dr Hortova’s scientific work has been widely recognised in the
field of Reproductive Biology with several key publications. She, with her
colleagues, described sperm cooperation for the very first time in rodent and
it was published in Nature (2002). The current major achievement is a discovery
of the interaction between CD46 and beta1 subunit of integrins in sperm during
sperm capacitation and acrosome reaction suggesting that these proteins are an
important part of sperm network involved in gamete interaction. Published
results are being of interest beyond the field of Reproduction, covering areas
of neuro-physiology, immunology, cell biology and even cancer research, by
stretching the understanding of the membrane fusion process in general
published in Sci Rep (2016). The published data has also a great value for
detection new aspects contributing to ever-so-growing human infertility, and
these proteins plan to be part of new detection kits used in Centres of
assisted reproduction, which is the current main focus of her team.
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