All staff and students are invited at attend Ke Tang's PhD confirmation review seminar. Ke's project title is "The mechanistic role of TLR2, TLR9 and AIM2 in gastric cancer".1pm-2pm, Tuesday, 13th December, Meeting Room 1, TRF Level 2, MHTP
Main Supervisor: Professor Brendan Jenkins
Associate Supervisor: Dr Daniel Gerald Croagh
Synopsis: Gastric cancer (GC) is the third most lethal cancer worldwide, and one of the classic examples of chronic inflammation-related carcinoma. The interaction between host innate immune system regulators (e.g. pattern recognition receptors, PRRs) and pathogens (e.g. Helicobacter pylori) contributes to gastric tumorigenesis. We focus on the mechanistic role of three such PRRs, TLR2, TLR9 and AIM2, in GC, and their relationships with hyper-activation of the signal transducer and activator of transcription (STAT) 3, to identify new GC molecular targets to serve as personalised biomarkers for early detection and/or treatment strategies.
Panel Chair: Dr Anthony Sadler
Independent Assessor: Dr James Harris
Independent Assessor: Dr Michael Gantier
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