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| Dr Holly Hutton |
Clinical Phenotyping of COPD exacerbations
Dr Martin MacDonald
Respiratory and Sleep Physician at Monash Medical
Centre
Postgraduate Student
Centre for Inflammatory Diseases
Exacerbations of
Chronic Obstructive Pulmonary Disease (COPD) are the second leading cause of
hospitalization in Australia. They can result from a variety of distinct
aetiological triggers but in clinical practice these are not systematically
evaluated. We have investigated the utility of comprehensive phenotyping
of exacerbations using both routine biomarker analysis and cutting edge CT
technology. Martin is a Respiratory and Sleep Physician at Monash Medical
Centre. Undergraduate and basic clinical training was undertaken in
Glasgow, UK before migration to Melbourne in 2006. My Specialty interests
are in complex airways disease and heart-lung interaction.
Targeting
the NLRP3 inflammasome in ANCA vasculitis
Dr Holly Hutton
Nephrologist at Monash Medical Centre
Postgraduate Student
Centre for Inflammatory Diseases
Activation of the NLRP3 inflammasome has been
implicated in a range of autoimmune and kidney diseases. This talk examines the
potential for a pathogenic role of the inflammasome in ANCA associated
vasculitis, which is the subject of my PhD research. As there are specific blocking
therapies available, the NLRP3 inflammasome may represent a specific and
appropriate target in the treatment of ANCA-associated vasculitis.
Future SeminarsTuesday 13 September - Dr Fabien Vincent
Tuesday 20 September - cancelled
Tuesday 27 September - Prof David Nikolic-Paterson
CiiiD seminars (Tuesdays at 1:00pm) - if you would like to be notified of the CiiiD seminars, please send an email to rebecca.smith@hudson.org.au.
A light lunch is served prior to the seminar at 11:45am in the seminar room foyer, level 2, TRF Building.
Further information available from CID Weekly Seminar Series website [http://www.med.monash.edu.au/scs/medicine/cid/seminar-series.html]
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