The FY16 Defense Appropriations Act provides $50
million (M) to the Department of Defense Peer Reviewed Cancer Research Program
(PRCRP) to support innovative, high-impact cancer
research. As directed by the Office of the Assistant Secretary of Defense
for Health Affairs, the Defense Health Agency, Research, Development, and
Acquisition (DHA RDA) Directorate manages the Defense Health Program (DHP)
Research, Development, Test, and Evaluation (RDT&E) appropriation.
The managing agent for the anticipated Program Announcements/ Funding
Opportunities is the Congressionally Directed Medical Research Programs
(CDMRP).
FY16 PRCRP Program Announcements and General
Application Instructions for the following award mechanisms are posted on the Grants.gov website.
Congressionally Directed Topic Areas: To be
considered for funding, applications for the FY16 PRCRP must address at least
one of the Topic Areas as directed by Congress. Research applications in
the areas of breast, prostate, lung (excluding mesothelioma), or ovarian cancer
will not be accepted.
The FY16 PRCRP Topic Areas are listed below:
· Bladder cancer (New for FY16)
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· Liver cancer
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· Pancreatic cancer
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· Colorectal cancer
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· Lymphoma (New for FY16)
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· Pediatric Brain Tumors (New for
FY16)
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· Immunotherapy* (New for FY16)
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· Melanoma and other skin cancers
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· Stomach cancer
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· Kidney cancer
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· Mesothelioma
|
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· Listeria vaccine for cancer
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· Neuroblastoma
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*As derived from the National Cancer Institute
Dictionary of Cancer terms1: Immunotherapy is a type of biological
therapy that uses substances to stimulate or suppress the immune system to help
the body fight cancer. Cancers studied under this topic area should be
within the scope of the Congressional language and the intent of the Program
Announcement(s).
The FY16 PRCRP Military Relevance Focus Areas are
listed below:
To address the cancer health needs of both deployed
and non-deployed personnel, their dependents, retirees, and Veterans, the FY16
PRCRP seeks to support studies that are responsive to the Military Relevance
Focus Areas listed below:
- Militarily
relevant risk factors associated with cancer (e.g., ionizing radiation,
chemicals, infectious agents, and environmental carcinogens)
- Gaps
in cancer prevention, screening, early detection, diagnosis, treatment,
and/or survivorship that may affect the general population but have a
particularly profound impact on the health and well-being of military
members, Veterans, and their beneficiaries
Applications that address exposures, conditions, or
circumstances that are unique to the military, or disproportionately
represented in a military beneficiary population, are the highest priority,
though any applications that address the above focus areas will be considered.
Career
Development Award- Preproposal due 6/8/16
Principal
Investigator (PI): Independent early-career investigator within 10 years
after completion of his/her terminal degree (excluding time spent in residency
or on family medical leave) by the time of the application submission deadline.
Designated
Mentor: Investigators at or above the level of Associate
Professor (or equivalent); must have a proven publication and funding record in
cancer research.
· Preproposal
is required; application submission is by invitation only.
·
Supports independent, early-career investigators to conduct impactful research
with the mentorship of an experienced cancer researcher
·
Must address at least one of the FY16 PRCRP Topic Areas
·
Strongly encouraged to address at least one of the FY16 PRCRP
Military Relevance Focus Areas
·
Preliminary data not required
Clinical
trials are not allowed
· Maximum funding
for the entire period of performance is $360,000 for direct costs (plus
indirect costs)
· Maximum period
of performance is 3 years
Idea
Award with Special Focus – Preproposal due 6/8/16
Independent
investigator with a faculty-level appointment (or equivalent).
· Preproposal
is required; application submission is by invitation only.
· Supports
innovative, untested, high-risk/potentially high-reward concepts, theories,
paradigms, and/or methods in cancer research that are relevant to Service
members, their families, and other military beneficiaries
·
Emphasis on innovation and military relevance/impact
·
Must address at least one of the FY16 PRCRP Topic Areas
·
Must address at least one of the FY16 PRCRP Military Relevance
Focus Areas
·
Preliminary data not required
Clinical
trials are not allowed
· Maximum funding
for the entire period of performance is $400,000 for direct costs (plus
indirect costs)
· Maximum period
of performance is 2 years
Translational
Team Science Award – Preproposal due 6/8/16
At least two and up to three PIs must partner in one overarching
correlative or translational research study.
At
least one of the PIs is encouraged to be a military or Department
of Veterans Affairs investigator.
· Preproposal
is required; application submission is by invitation only.
·
Supports translational correlative studies associated with an ongoing or
completed clinical trial and/or translational study that can lead to a
future clinical trial or clinical application in cancer research that is
relevant to Service members, their families, and other military beneficiaries
·
Not intended to support high throughput
screenings, sequencing, etc.
·
Must address at least one of the FY16 PRCRP Topic Areas
·
Must address at least one of the FY16 PRCRP Military Relevance
Focus Areas
·
Preliminary data is required
Clinical
trials are not allowed
· Maximum funding
for the entire period of performance is $1,000,000 for direct costs
(plus indirect costs)
· Maximum period
of performance is 3 years
A
pre-application is required and must be submitted through the CDMRP electronic
Biomedical Research Application Portal (eBRAP) website (https://eBRAP.org) prior to the
pre-application deadline. All applications must conform to the final
Program Announcement(s) and General Application Instructions available for
electronic downloading from the Grants.gov website. Applications must be
submitted through the federal government’s single-entry portal,
Grants.gov. The application package containing the required forms for
each award mechanism will also be found on Grants.gov. A listing of all
USAMRMC funding opportunities can be obtained on the Grants.gov website by
performing a basic search using CFDA Number 12.420.
Requests
for email notification of the Program Announcement(s) release may be sent to help@eBRAP.org. Email notifications of funding
opportunities are sent as a courtesy and should not be used as a sole source of
notification; applicants should monitor Grants.gov for official postings of
funding opportunities.
For
more information about the PRCRP or other CDMRP-administered programs, please
visit the CDMRP website (http://cdmrp.army.mil).
Point of Contact:
CDMRP Help Desk
All ECRs are
encouraged to consider this exciting opportunity.
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