Position vacant - Hudson Institute

Dr Minni Anko (CRH/CCR) is currently recruiting for a Postdoctoral Scientist (RES Level A) for a 12 month full-time contract.

Casual Technical Assistant Position

An opportunity has arisen for a casual (1-2 days) Technical Assistant within the Department of Surgery in the School of Clinical Sciences at Monash Health. This position will support the research activities of the Melbourne Shoulder and Elbow Centre based in Brighton.

Monash Health HREC & SSA Coordinator

Monash Health are recruiting an additional team member for their expanding Research Support Services team. The role is HREC & SSA Coordinator, 0.8 EFT.

Post-Doctoral Fellow : Human T lymphocyte/ CAR-T cells: Cartherics Pty Ltd

Position Description: Cartherics is seeking a talented Post-Doctoral Fellow to help implement its very active research program in Chimeric Antigen Receptor (CAR) -T based immunotherapies.

CAR-T cells have rapidly evolved as a revolution in anti-cancer treatments. Cartherics primary platform is to use induced pluripotential stem cells (iPSC) to embed a TCR specificity. These T-iPSC will then be gene edited with specific CAR’s, and induced to differentiate into cytotoxic T cells. Central to the success of these platforms will be to maximise T cell expansion and differentiation in sufficient effective numbers for clinical trials. This project will explore the forward reprograming of iPSCs using transcription factors to induce T cell differentiation and to optimise their function. The successful applicant will thus have a strong background in immunology related tissue culture and a preference for experience preferably with human iPSCs and/or T cells. They will have a desire to succeed in a competitive environment and relish the challenge of helping to implement new technologies and equipment as necessary; the rewards will be substantial. Accordingly, the successful applicant will have extensive experience in immunology-based research techniques.

Education/Qualifications: The appointee will either have a PhD or experience as a research assistant, in a relevant field preferably including iPSCs from a recognised university or research institute. They will be working within a dynamic team but as a Post-Doctoral appointment, they will be expected to contribute in a leadership capacity. Company Description Cartherics Pty Ltd is an exciting new Melbourne-based start-up biotechnology company, developing the next generation immune therapeutic approach to treat cancer. The Company’s objective is to identify and expand T cells with their own cancer recognizing T Cell Receptors (TCRs), then use sophisticated gene editing to empower these cells with additional cancer-specific recognition and activation molecules (CAR-T). Cartherics will use stem cell technology to exponentially expand these “cancer smart” killer cells.

The laboratories are located within the new facilities of the Monash Health Translation Precinct at Monash Medical Centre, Clayton, Vic 3168. Send application with CV including potential referees to: Karen Loudon Karen.loudon@hudson.org.au

Closing date 15 April 2018.

Cartherics Research Vacancy

Research Assistant : Position description
Cartherics is a new, privately owned biotechnology company, focussed on developing cutting edge technologies to empower the immune system to specifically target and eradicate cancer. The focus technology is the ground-breaking technology: Chimeric Antigen Receptor T cells (CAR-T), which have a profound ability to seek and destroy cancer cells. The company has 10 full-time research staff, an Executive Assistant and several expert advisors and is closely linked to the Hudson Institute of Medical Research. It is supported by strong private investment and two recently awarded, highly prestigious government grants: Victorian Government Medical Research Acceleration Award to promote the implementation of a CAR-T clinical trial and a Commonwealth Government CRC-P grant to develop a next generation immune- cell therapy “as an off the shelf “ product for treating gastric and ovarian cancers. The company’s labs and offices are located in the MHTP Building, next to the Hudson Institute of Medical Research, 27-31 Wright Street, Clayton 3168.

The company is seeking to appoint a Research Assistant to work closely with the company post-docs on the major research themes. The successful applicant will have the appropriate “hands on” skills in one or more of the following technologies:

(i)production, enrichment and cell transduction of lentivirus and generalmolecular biology methods;
(ii)isolation, activation, expansion and functional analysis of humanblood T cells, including use of multi-parameter flow cytometry;
(iii)Experience in production, maintenance and directed differentiation ofiPSC, ideally with an understanding of T cell requirements.

The successful applicant will have at least a Bachelor degree with Honours in Science or Biomedical Science or equivalent and ideally 3 or more years of appropriate laboratory experience. They will relish working in a challenging, dynamic, interactive and very exciting environment.

Applicants should submit their CV with nominated referees together with a letter outlining their suitability, to Karen Loudon at karen.loudon@hudson.org.au

Position closes: April 15th 2018.