Wed 28 June, 2pm-3pm
- Hudson Institute Level 3 - Board Rooms
IFNs were identified as
antiviral proteins more than 50 years ago and since then have been shown to
regulate cell proliferation, survival, migration and specialised functions.
Consequently they are involved in numerous homeostatic and pathological processes
including infections, cancer, autoimmunity, inflammation and metabolic
disorders. These cytokines are also used as therapeutics in diseases such as
chronic viral infections, cancer and multiple sclerosis. IFNs potentially
regulate the transcription of up to 2000 genes in an IFN subtype, dose, cell
type and stimulus dependent manner.
The Interferome database
integrates information from high-throughput experiments to gain a detailed
understanding of the various IFN activated pathways that regulate subsets of
genes, with the aim to enhance our understanding of pathophysiological
processes.
In this seminar Dr Ross Chapman, from the Centre for Innate Immunity and Infectious
Diseases, will introduce you to the Interferome online database and
demonstrate analysis tools available on this application.
For more information or to
join the bioinformatics affinity group please contact: roxane.legaie@monash.edu
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