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Monday, 8 August 2016

Seeking children 5 - 10 years to participate in sleep research

The Ritchie Centre (TRC) is looking  for  children  between  the ages of  5  and  10  years to participate as a control group in research sleep studies.

The TRC is carrying out studies on the effect of breathing difficulties at night on learning and behaviour. We are looking for non-snoring 5-10 year old volunteers to serve as a comparison group to the children with sleep disordered breathing.

Children who participate will be asked to wear a watch-like device for one week to assess their usual sleep patterns. They will also participate in a learning and memory assessment and have an overnight sleep study ALL CONDUCTED IN YOUR OWN HOME. There will be no need to come into the laboratory. We will come to you.

What do you get  out of it? We will provide you with a full report of your child’s behaviour, learning and memory assessments so that you can see how they are developing in relation to their peers. We will also provide you with the report of the sleep study if you are interested.

The results from this study will determine if learning potential is intact in children with sleep disordered breathing and will provide new information regarding potential new non-surgical treatment strategies.

For further information please contact: Dr Sarah Biggs, The Ritchie Centre Phone: 9594 4759 Email: sarah.biggs@monash.edu
Or visit our information page at www.monashchildrenshospital.org

Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1Ra

Claudia Nold et al. published in the American Journal of Respiratory Cell and Molecular Biology.

Read article here.

Neonatal infections: Case definition and guidelines for data collection, analysis, and presentation of immunisation safety data

Jim Buttery et al. published in Vaccine.

Read article here.

High-dose therapy and autologous stem cell transplantation may only be applicable to selected patients with secondary CNS diffuse large B-cell lymphoma.

Stephen Opat et al. published in the British Journal of Haematology.

Read article here.

Maternal creatine supplementation during pregnancy prevents acute and long-term deficits in skeletal muscle after birth asphyxia: a study of structure and function of hind limb muscle in the spiny mouse.

Hayley Dickinson et al. published in Pediatric Research.

Read article here.

Review article: Effectiveness of ultra-brief interventions in the emergency department to reduce alcohol consumption: A systematic review.

Diana Egerton-Warburton et al. published in Emergency Medicine Australasia: EMA

Read article here.

Influence of fracture geometry on bone healing under locking plate fixations: A comparison between oblique and transverse tibial fractures

Peter Ebeling et al. published in Medical Engineering and Physics.

Read article here.

Decorin expression is decreased in first trimester placental tissue from pregnancies with small for gestation age infants at birth

Padma Murthi et al. published in Placenta.

Read article here.

Monday, 1 August 2016

Need for improved rehabilitation assessment for patients experiencing stroke in Australia

A/Prof Cadilhac
Australian patients with stroke are not being adequately assessed for rehabilitation due to health professionals’ preconceived beliefs about suitability, according to latest research from UniSA undertaken in collaboration with Monash University.

Stroke Foundation data from 2011 and 2013 indicated that fewer than half the patients with acute stroke in Australian hospitals were assessed for rehabilitation.

“These results compare unfavourably with audits conducted the UK and the US where about 90% of patients have received rehabilitation assessments,” said study author Associate Professor Dominique Cadilhac, Head of Translational Public Health and Evaluation Division, Stroke and Ageing Research in the School of Clinical Sciences at Monash Health.

“Australian clinical guidelines include the good practice point that every patient with stroke, who is not for palliative care, should be assessed for further rehabilitation.”

To address concerns regarding the low proportion of Australian patients with stroke being assessed for rehabilitation, the Australian Stroke Coalition developed an evidence-based and patient-centred Rehabilitation Assessment Tool in 2011.

Associate Professor Cadilhac said the Assessment Tool was designed to guide health professionals to make objective decisions regarding the rehabilitation requirements of every patient with stroke admitted to hospital.

“Our latest research reveals that health professionals working on acute stroke units believe there are not enough rehabilitation services to meet the needs of patients with stroke.”

“We’ve also shown that patients with rehabilitation needs are not always referred to rehabilitation services, and beliefs about the purpose of rehabilitation assessments vary between health professionals,” said Associate Professor Cadilhac.

Among the health professionals interviewed within the 10 study stroke units often the patients with severe stroke, stroke-related cognitive deficits or co-existing dementia were considered unlikely to benefit from rehabilitation and so were not referred for assessment.

“It is also significant that two-thirds of patients with stroke in Australian hospitals do not receive documented assessments of mood or continence problems.”

“Rehabilitation interventions can be effective for addressing problems with mood or urinary incontinence after stroke, but without being provided with the opportunity for rehabilitation assessment, it is unlikely that appropriate management plans will be organised for such conditions,” said Associate Professor Cadilhac.

“Consistent use of the Rehabilitation Assessment Tool will enable more holistic plans to be developed for each patient in the early post-stroke period, which we believe will lead to enhanced clinical outcomes.”

 For further information see: http://australianstrokecoalition.com.au/site/media/ASC-Assessment-for-Rehabilitation-Manual-and-Decision-Making-Tool-final2.pdf

Women affected by early menopause to benefit from Monash research

Professor Teede
A Monash-led research project aimed at treating early menopause has received funding from the National Health and Medical Research Council (NHMRC).

The early menopause project is being driven by researchers in the Faculties of Medicine and Arts. The Monash team members include the Director of the Monash Centre for Health Research and Implementation (MCHRI), Professor Helena Teede; the Director of Social Studies of Health and Medicine Research Program, Associate Professor Renata Kokanovic, and Associate Professor Amanda Vincent of MCHRI.

Professor Teede said that early menopause, defined as menopause before age 45, affects more than 10 per cent of Australian women. She said women afflicted with early menopause are at greater risk of premature death and also suffer negative impacts on their quality of life.

“Our project aims to bridge the knowledge gaps within the community on early menopause and to improve health professionals’ understanding and management of the condition. Lack of understanding about early menopause can delay diagnosis, cause variation in care and limit risk perception,” Professor Teede said.

“We will undertake epidemiological research to clarify and evaluate the long-term impacts of early menopause as well as conduct qualitative research to better understand women’s experiences of early menopause,” she said.

Associate Professor Kokanovic said project outcomes will include the development of website information resources that outline the health implications of early menopause.

“The information we acquire through our research will be available on the respected online site, Healthtalk Australia,” Associate Professor Kokanovic said.

The information compiled, she said, will be evidence-based and include links to other relevant resources.

Christmas in July at SCS

A big thank you to all who attended the Christmas in July event last Friday, hosted by the SCS Social Committee -  and a big thank you to those who brought a plate to share. The lunch was a success with approximately 30 attendees enjoying a Japanese inspired Christmas lunch along with a selection of cakes. 

Stay tuned for upcoming social events brought to you by the SCS Social Committee! 

CID and CiiiD seminars, 2 August

Dr Greg Tesch
"Therapeutic Targeting of Inflammation in Diabetic Nephropathy"
12-1pm in the TRF Seminar Room 1, presented by Dr Gregory Tesch

"NOD1 sensing of Helicobacter pylori promotes production of mature IL-18 in gastric epithelial cells"
1-2pm in Seminar Room 1 of the TRF.  Presented by Dr Le Son Tran and chaired by  Dr Liang Yu

The CID seminar, held Tuesday .  Information regarding the CID seminar series is available at http://www.med.monash.edu.au/scs/medicine/cid/seminar-series.html

Lunch will be served at 11:45am in the foyer of the TRF building.



Grand Rounds, Immunotherapy in toxicology: Not always so FAB!, 3 August

Unit: Emergency               
Presenters: Professor Andis Graudins
Date: Wednesday 3 August 2016
Time: 12.30pm to 1.30pm

Venue: Main Lecture Theatre, Monash Medical Centre, Clayton.

Medical Research Future Fund (MRFF) - Public Consultation (Melbourne - Thursday 4 August)

The Australian Medical Research Advisory Board is undertaking consultations to develop the Australian Medical Research and Innovation Strategy and related Priorities to improve the wellbeing of Australians through health and medical research and innovation.

At its inaugural meeting on 4 May 2016, the Advisory Board agreed to a two stage consultation process to ensure extensive input from those who deliver, use or stand to benefit from health services and health and medical research. The first stage of the consultation process was a call for written submissions on the development of the Strategy and Priorities. 

The Advisory Board has considered these submissions and developed a draft framework that will be used to determine the Strategy and Priorities. This framework will be discussed during this second stage public consultation.

Details on the various public consultations is available at: http://health.gov.au/internet/main/publishing.nsf/Content/mrff

The Melbourne session is being held on Thursday 4 August, 9-11am at WEHI (Parkville).

To register your attendance at this event, please go to: 

CD1-Reactive T cells Mediate Human Response to Tuberculosis Infection, Tuesday, August 9

Tuesday, August 9 from 12pm to 1pm in Seminar Room 1, Level 2, TRF.

The speaker will be Professor D. Branch Moody, from Brigham and Women's Hospital, Harvard Medical School.


















If you wish to make an appointment with Prof Moody, please email rebecca.smith@hudson.org.au


PerkinElmer PCI seminar, 9 August


Wearable and Point of Care Biodiagnostics Workshop, 15 August

8.30am-5pm, G29/G30, New Horizons, 20 Research Way, Monash University Clayton campus

This free workshop will focus on the latest developments in wearable technologies designed for point of care diagnostics and physiological monitoring. Supported by the ARC Centre of Excellence in Convergent Bio-Nano Science & Technology, the Monash Institute for Medical Engineering (MIME), Monash Chemical Engineering Department, and Harbin Institute of Technology, the workshop will include presentations by 20 invited experts. The full program will be released shortly and catering will be provided throughout the day.

Please RSVP (for logistics/catering purposes) online using the “MIME16” coupon for FREE rego by Monday 10th August 2016 via the following link: https://www.eventbrite.com.au/e/wearable-and-point-of-care-biodiagnostics-symposium-tickets-25500331177

Flyer with details here or see MIME website here: http://www.monash.edu/mime/events/index.html 

MHTP Graduate Research Expo events for prospective PhD and Hons students: 3 and 9 August






































For more information and registration please visit:
 http://www.med.monash.edu.au/scs/students/higher-degrees-research.html

The Ritchie Centre 2016 Colloquium and Public Forum “Cell Therapy & Translational Research”, 25-26 August


Cell therapies and regenerative medicine are rapidly growing industries identified by the National Institutes of Health in the USA as the next pillar in modern medicine.  The awareness of the innate capacity of the fetus to repair and regenerate tissues is being used to develop unique models of organ and tissue regeneration using stem cells. The Ritchie Centre has established the Cell Therapies Platform within the Translational Research Facility at the Monash Health Translation Precinct to capitalise on this opportunity and currently leads a number of Phase I and Phase II stem cell clinical trials.  


This year’s Ritchie Colloquium will highlight clinical translation research in Cell Therapy and Regenerative Medicine being undertaken by members of The Ritchie Centre and by national and international colleagues. The Ritchie Centre Public Forum international panel of experts will address topical issues of Stem Cell Therapies and discuss clinical trials currently being undertaken and the potential of future treatments.

Change x Unzipped - A Victorian Global Health Collaboration, 6-7 August

Introducing an exciting new global health collaboration between medical students at Monash, Melbourne and Deakin, Change x Unzipped is a two-day global health symposium held in Melbourne on Saturday August 6 and in Geelong on Sunday August 7. With inputs from professionals across many disciplines, be prepared to gain a different perspective on global health issues and engage in interactive workshops and panel discussions.

Change, on Saturday, will focus on the intersection of the UN Sustainable Development Goals (SDGs) and Global Health. Be informed during an incredible morning of speakers before taking action in an afternoon of collaborative, engaging workshops. Global Health Unzipped, on the Sunday, seeks to empower individuals to take action in global health with speakers and facilitated panel discussions.

Tickets are $20 per day
Head to http://www.changexunzipped.org to find out more and register today!

Like the FB page to find out about speakers, food, and more! https://www.facebook.com/changexunzipped/

Global Health Unzipped FB event page: https://www.facebook.com/events/1120059171385959/