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Monday 30 May 2016

U.S. Department of Defense (DoD) Lung Cancer Research Program Funding Opportunity

The FY16 Defense Appropriations Act provides $12 million (M) to the Department of Defense (DoD) Lung Cancer Research Program (LCRP) to support innovative, high-impact lung cancer research.  As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency, Research, Development, and Acquisition Directorate manages the Defense Health Program Research, Development, Test, and Evaluation appropriation.  The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).
FY16 LCRP Program Announcements and General Application Instructions for the following award mechanism is posted on the Grants.gov website. 
Areas of Emphasis:  The FY16 LCRP encourages research projects that specifically address the critical needs of the lung cancer community in the following Areas of Emphasis:
       Identify or develop noninvasive or minimally invasive tools to improve the detection of the initial stages of lung cancer.
       Identify, develop, and/or build upon already existing tools for screening or early detection of lung cancer.  Screening may include, but is not limited to, imaging modalities, biomarkers, genetics/genomics/proteomics/metabolomics/transcriptomics, and assessment of risk factors.
       Understand the molecular mechanisms of initiation and progression to clinically significant lung cancer. 
       Identify innovative strategies for prevention and treatment of early and/or localized lung cancer.
       Understand predictive and prognostic markers to identify responders and nonresponders.
       Understand susceptibility or resistance to treatment.
       Understand contributors to lung cancer development other than tobacco.

Military Relevance:  The FY16 LCRP strongly encourages research projects that are relevant to the health care needs of military Service members, Veterans, and their families.  Investigators are encouraged to consider the following characteristics as examples of how a project may demonstrate military relevance:
       Use of military or Veteran populations or data in the proposed research.
       Collaboration with DoD or Department of Veterans Affairs investigators.
       Involvement of military consultants (Army, Air Force) or specialty leaders (Navy, Marine Corps) to the Surgeons General in a relevant specialty area.
       Description of how the knowledge, information, products, or technologies gained from the proposed research could be implemented in a dual-use capacity to address a military need that also benefits the civilian population.
       Explanation of how the project addresses an aspect of lung cancer that has direct relevance to military Service members, Veterans, or other military health system beneficiaries, including environmental exposures other than tobacco.

Concept Award
Investigators at all academic levels
Supports highly innovative, untested, potentially groundbreaking concepts in lung cancer
Emphasis on innovation
Clinical trials not allowed
Preliminary data discouraged
Military relevance strongly encouraged
Maximum funding of $100,000 in direct costs (plus indirect costs)
Period of performance should not exceed 1 year
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline.  All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website.  The application package containing the required forms for each award mechanism will also be found on Grants.gov.  A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.  

Applications must be submitted through the federal government’s single-entry portal, Grants.gov.    For email notification when Program Announcements are released, go to the CDMRP website (http://cdmrp.army.mil) and select Subscribe to Funding Opportunities & Program Communications.  For more information about the LCRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).


For questions about the research programs, please contact the MRO Research Grants & Contracts Team (adm-researchgrants.contracts@monash.edu).

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