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| Dr Shavi Fernando |
Congratulations to Dr Shavi Fernando on completion of his PhD at Monash University.
Shavi conducted a pilot double blind placebo controlled
dose-response randomised trial assessing the impact of melatonin on the
outcomes of assisted reproductive technology (the MIART trial).
"I randomised
women undergoing their first cycle of IVF to receive an oral placebo or any one
of three different doses of melatonin during ovarian stimulation," Shavi said.
"My study found that
oral supplementation of melatonin in this population results in a clinically
and statistically significant dose-dependent increase in serum and follicular
fluid concentrations of melatonin."
"Despite this, there were no similar
increases in daytime sleepiness or changes in night time sleep quality;
ultrasound markers of ovarian response; or oocyte or embryo number or quality," he said.
Importantly, the pilot study found no significant benefit of melatonin on clinical
pregnancy or live birth rates in women undergoing treatment with assisted
reproductive technology.
Shavi is currently working clinically in both the public and
private sector as a specialist obstetrician and gynaecologist. His PhD and
interest in medical education has also helped him secure a role as the Director
of curriculum and assessment (Women’s Health) at Monash University. In
addition, he is a Training supervisor for FRANZCOG trainees at Monash Health.
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