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Monday 23 April 2018

Hudson Seminar Series - Dr C.Glenn Begley - 26th April

This week's Hudson seminar will be held in Seminar Rooms 1 & 2, Level 2, TRF Building on Thursday 26th April 12pm-1pm.
Our speaker will be Dr C. Glenn Begley MB BS PhD FRACP FRCPA FRCPath FAHMS;
CEO of BioCurate Pty Ltd.

He will be presenting 'Challenges facing Translational Research across the Yarra, and around the World'

As medical researchers, we all want to make a difference.  We all want to make discoveries that have a real impact on human health. There are however many obstacles to achieving this goal.
In an effort to address some of these, Monash University and the University of Melbourne have created an independent company, BioCurate charged with taking the medical research from the two Universities and translating that research into therapeutics of clinical and commercial value.
Over the last 6 months, BioCurate has had the privilege of reviewing over 50 research projects. Those reviews have revealed themes common to academic research worldwide.
Unfortunately, however, the rewards that currently apply within the worldwide academic system provide a perverse set of incentives that reward flashy science with little regard for the quality, robustness or reliability of the work.  That is particularly the case for papers published in the “top tier” journals. In this presentation, I will review and ‘dissect’ several high profiles, highly cited publications that illustrate the problem. These highly cited publications, from famous investigators and their laboratories, typically fail because experiments were not performed by blinded investigators, positive and negative controls were not used, experiments were not repeated, reagents were not validated, only select data was shown, and data analysis was inappropriate.
This is a systemic problem and guarantees that a focus on rigour and reproducibility at the very heart of the BioCurate’s endeavours.

A light lunch and refreshments will follow this presentation. 

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