Monday 4 June 2018

Hudson seminar: 'From protein domain dynamics to new diagnostic markers for gamete selection that enhance human assisted reproduction success', 7 June

This week's Hudson seminar will be held in Seminar Rooms 1 & 2,  TRF Building on  Thursday 7th June, 12pm-1pm.

Our speaker will be Dr Katerina Hortova, PhD.
Group of Reproductive Biology, Institute of Biotechnology, Czech Academy of Sciences, BIOCEV, Czech Republic; Department of Zoology, Faculty of Science, Charles University, Prague, Czech Republic

She will be presenting 'From protein domain dynamics to new diagnostic markers for gamete selection that enhance human assisted reproduction success'

Dr Hortova’s scientific work has been widely recognised in the field of Reproductive Biology with several key publications. She, with her colleagues, described sperm cooperation for the very first time in rodent and it was published in Nature (2002). The current major achievement is a discovery of the interaction between CD46 and beta1 subunit of integrins in sperm during sperm capacitation and acrosome reaction suggesting that these proteins are an important part of sperm network involved in gamete interaction. Published results are being of interest beyond the field of Reproduction, covering areas of neuro-physiology, immunology, cell biology and even cancer research, by stretching the understanding of the membrane fusion process in general published in Sci Rep (2016). The published data has also a great value for detection new aspects contributing to ever-so-growing human infertility, and these proteins plan to be part of new detection kits used in Centres of assisted reproduction, which is the current main focus of her team.

A light lunch and refreshments will follow this presentation. 

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