1 March at 3pm, seminar room, level 4, Block E, Monash Medical Centre
Thesis title: Characterisation
of X-linked inhibitor of apoptosis protein in ovarian granulosa cell tumours
Synopsis: Granulosa cell tumours (GCT) represent a large subset of sex-cord stromal tumours which contribute to ~8% of all ovarian malignancies. The aim of my PhD project is to investigate PPAR gamma and XIAP as potential targets for combination treatment of GCT. I will also identify and manipulate the unusual and distinctive patterns of expression of key genes involved in cell survival, which will provide us with both prognostic information and potential new and novel therapeutic targets for treatment of these tumours.
Supervisors: Prof. Peter J Fuller and Dr Simon Chu
Panel chair: Dr Peter Stanton
Independent assessors: A/Prof Tim Cole and Prof Vincent Harley
Synopsis: Granulosa cell tumours (GCT) represent a large subset of sex-cord stromal tumours which contribute to ~8% of all ovarian malignancies. The aim of my PhD project is to investigate PPAR gamma and XIAP as potential targets for combination treatment of GCT. I will also identify and manipulate the unusual and distinctive patterns of expression of key genes involved in cell survival, which will provide us with both prognostic information and potential new and novel therapeutic targets for treatment of these tumours.
Supervisors: Prof. Peter J Fuller and Dr Simon Chu
Panel chair: Dr Peter Stanton
Independent assessors: A/Prof Tim Cole and Prof Vincent Harley
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